Nexium is used to treat gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the esophagus (food pipe between the mouth and stomach) in adults and children 1 year of age and older. Esomeprazole is used to treat the symptoms of GERD, allow the esophagus to heal, and prevent further damage to the esophagus. Esomeprazole is also used to decrease the chance of getting an ulcer in people who are taking nonsteroidal anti-inflammatory drugs (NSAIDs). It is also used with other medications to treat and prevent the return of stomach ulcers caused by a certain type of bacteria (H. pylori). Esomeprazole is also used for long-term treatment of conditions (such as Zollinger-Ellison Syndrome) in which the stomach makes too much acid. Esomeprazole is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.
How should this medicine be used
Esomeprazole comes as a delayed-release (long-acting) capsule to take by mouth or to open, mix with water, and give through a feeding tube and as granules to mix with water and take by mouth or give through a feeding tube. Esomeprazole is usually taken once a day at least 1 hour before a meal.When esomeprazole is used to treat some conditions in which the stomach makes too much acid, it is taken twice a day. Take esomeprazole at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take esomeprazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Swallow the capsules whole; do not split, chew, or crush them. If you cannot swallow the capsule, put 1 tablespoon of cool, soft applesauce in an empty bowl. Open one esomeprazole capsule and carefully sprinkle the pellets onto the applesauce. Mix the pellets with the applesauce, and swallow the entire tablespoonful of the applesauce and pellet mixture immediately. Do not chew the pellets in the applesauce. Do not save the pellets and applesauce for later use.
To mix the granules, follow these steps:
1. Place 1 tablespoon, 15 mL of water into a cup.
2. Open the esomeprazole packet and empty the granules into the cup containing the water.
3. Stir the granules into the water and leave the mixture alone for 2 to 3 minutes so that it will thicken.
4. Stir the mixture again, and drink all the mixture within 30 minutes.
5. If any material remains in the cup after drinking, add some more water and stir. Drink all of the mixture immediately.
Before taking nexium
Tell your doctor and pharmacist if you are allergic to esomeprazole, lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), rabeprazole (AcipHex), or any other medications.
* tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention atazanavir (Reyataz); anticoagulants ('blood thinners') such as warfarin (Coumadin); antifungals such as ketoconazole (Nizoral) and voriconazole (Vfend); clopidogrel (Plavix); digoxin (Digitek, Lanoxicaps, Lanoxin); and iron supplements. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
* tell your doctor if you have or have ever had liver disease.
* tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking esomeprazole, call your doctor.
* you may take antacids with esomeprazole. If you feel you need an antacid, ask your doctor to recommend one and to tell you when and how to take it.
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